With the advent of CRISPR technologies, almost at any specific locus in any genome of animal or plant, large-size DNA fragment can be inserted or replaced seamlessly following the occurrence of CRISPR nuclease-produced double-strand break (DSB) and donor DNA, and the induction of homology-directed repair (HDR) can be realized.At present, the homolo
Optimal capacitor placement in northern region of Bangladesh transmission network for voltage profile improvement
This paper solves the problem of optimal placement Alarm Clocks of shunt capacitors in the northern region of Bangladesh transmission network.During network augmentation event like very high inductive reactive load condition, the weakened voltage profile of the buses can be compensated by optimum allocation of the capacitor banks.In this regard, th
Genomic Profiling of Antimicrobial Resistance Genes in Clinical Salmonella Isolates from Cattle in the Texas Panhandle, USA
Rising antimicrobial resistance (AMR) in Salmonella serotypes host-adapted to cattle is of increasing concern to the beef and dairy industry.The bulk of the existing literature focuses on AMR post-slaughter.In comparison, the understanding of AMR in Salmonella among pre-harvest cattle is still limited, particularly in Texas, which ranks top five in
The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment
Sodium taurocholate cotransporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus infection of Baby Creams host hepatocytes.Previously, many studies confirmed that the NTCP p.Ser267Phe variant was a protective factor against HBV-related disease progression.We therefore designed this study to investigate whether the NTCP p.